Radiologic Findings in Gabapentin-Induced Myositis.

نویسندگان

  • Tyler Michael Coupal
  • David Ross Chang
  • Kevin Pennycooke
  • Hugue Alcide Ouellette
  • Peter Loren Munk
چکیده

Throughout recent years, Gabapentin has become increasingly used for the treatment of neuropathic pain. We report on a case of a 31 year old female who presented to the emergency department with unilateral leg pain, weakness, and swelling after increasingly titrating her Gabapentin dosage over three weeks. Magnetic resonance imaging confirmed the presence of myositis confined to the left thigh and the patient's symptoms and laboratory abnormalities resolved following Gabapentin cessation. While Gabapentin-induced myositis and rhabdomyolysis is a rare entity, it should be a diagnostic consideration for radiologists, particularly in the absence of infection or trauma.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gabapentin prevents oxaliplatin-induced central sensitization in the dorsal horn neurons in rats

Objective(s): The present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. Materials and Methods: Oxaliplatin (5 mg/kg) or saline was administered to adult male Sprague-Dawley rats.  Gabapentin (60 mg/kg, IP) or vehicle was injected daily. Mechanical allodynia was assessed us...

متن کامل

Effect of two types of exercise combined with atorvastatin on AMPK and (Cytochrome c) expression of cardiac myositis in elderly rats

Effect of two types of exercise combined with atorvastatin on AMPK and SYTOCHOROM C expression of cardiac myositis in elderly rats with type 2 diabetes One of the most common physical problems in old age is chronic diabetes. this issue is more intense and sensitive. Therefore the aim of this study was to investigative the combined effect of two types of exercise with atorvastatin on the on the...

متن کامل

Radiologic findings in seven patients with fibrodysplasia ossificans progressiva.

Fibrodysplasia ossificans progressiva is a rare and disabling syndrome, which is characterized by heterotopic ossifications and skeletal deformities. So far, around 200 patients with fibrodysplasia ossificans progressiva have been reported in the world literature. Herein, we analyze the clinical records of 7 known cases of fibrodysplasia ossificans progressiva from Iran who were admitted to the...

متن کامل

Cellular and behavioral interactions of gabapentin with alcohol dependence.

Gabapentin is a structural analog of GABA that has anticonvulsant properties. Despite the therapeutic efficacy of gabapentin, its molecular and cellular mechanisms of action are unclear. The GABAergic system in the central nucleus of the amygdala (CeA) plays an important role in regulating voluntary ethanol intake. Here, we investigated the effect of gabapentin on GABAergic transmission in CeA ...

متن کامل

گزارش یک مورد سایکوز وابسته به مصرف گاباپنتین

Gabapentin was first approved for treatment of epilepsy by FDA, but later it received more attention due to its effects on pain relief, especially neuropathic pain and post-herpetic neuralgia, and in treatment of anxiety and insomnia. The most common side effects of gabapentin include somnolence, ataxia, and fatigue. However, no studies have reported gabapentin induced psychotic disorder. Here,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of radiology case reports

دوره 11 4  شماره 

صفحات  -

تاریخ انتشار 2017